Course Description
A) Membrane structure and function (Structure of model membrane, lipid bilayer and membrane of sorting and regulation of intracellular transport,electrical properties of membranes)
B) Structural organization ande protein diffusion, osmosis, ion channels, active transport, membrane pumps, mechanism function of intracellular organelles (Cell wall, nucleus, mitochondria, Golgi bodies, lysosomes, endoplasmic reticulum, peroxisomes, plastids, vacuoles, chloroplast, structure & function of cytoskeleton and its role in motility).
C) Cell division and cell cycle (Mitosis and meiosis, their regulation, steps in cell cycle, regulation and control of cell cycle).
D) Cell signaling Hormones and their receptors, cell surface receptor, signaling through G-protein coupled receptors, signal transduction pathways, second messengers, regulation of signaling pathways, bacterial and plant two component systems, light signaling in plants, bacterial chemotaxis and quorum sensing.
E) Cellular communication. Regulation of hematopoiesis, general principles of cell communication, cell adhesion and roles of different adhesion molecules, gap junctions, extracellular matrix, integrins, neurotransmission and its regulation. Cancer Genetic rearrangements in progenitor cells, oncogenes, tumor suppressor genes, cancer and the cell cycle, virus-induced cancer, metastasis, interaction of cancer cells with normal cells, apoptosis, therapeutic interventions of uncontrolled cell growth.
F) Host parasite interaction. Recognition and entry processes of different pathogens like bacteria, viruses into animal and plant host cells, alteration of host cell behavior by pathogens, virus-induced cell transformation, pathogen-induced diseases in animals and plants, cell-cell fusion in both normal and abnormal cells.
Who This Course is for
This course is for CSIR-NET aspirants and students pursuing post-graduation in different biological sciences having cell biology in their curriculum. This course is designed to provide an in and out knowledge of basic and analytical concepts in Cell Biology.
